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Official websites use. Share sensitive information only on official, secure websites. Email: pierre-emmanuel. All patients and controls had at least one sign of portal hypertension and CT available within 1 year of liver biopsy. Liver histological lesions found in patients with PSVD include obliterative portal venopathy, hepatoportal sclerosis, nodular regenerative hyperplasia, and incomplete septal cirrhosis. Moreover, clinical features and histological lesions associated with morphological changes at CT have not been investigated.
None of the patients refused permission for use of their case records for medical research. All biopsies from patients with PSVD were reviewed by an expert pathologist to rule out cirrhosis and to assess the presence of elementary lesions classified according to prespecified criteria Table S1.
Extrahepatic conditions associated with PSVD were classified into categories detailed in Table S2 , according to previous reports. Each patient with PSVD was randomly matched according to severity of ascites and to year of liver catheterization with 2 patients with histologically proven cirrhosis and signs of portal hypertension same as patients with PSVD , who also underwent hepatic vein catheterization between and June at our center. We chose to stratify on ascites, because this feature is the only one associated with survival both in patients with PSVD and in patients with cirrhosis.
We included only patients with cirrhosis related to excessive alcohol consumption, chronic B or C virus infection, and metabolic associated fatty liver disease, as it represents most of the patients with cirrhosis seen in clinical practice.
As for the learning cohort, patients with cirrhosis were included if they had undergone a CT within 1 year of liver sample collection.