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Official websites use. Share sensitive information only on official, secure websites. E-mail: emmanuel. The Austrian gynecologist Ernst Wertheim was a pioneer in the surgical treatment of cancer.
However, in the early s, a meta-analysis of randomized trials revealed that radiotherapy and concomitant chemotherapy without surgical removal of the uterus were more effective in the historical treatment of advanced cervical cancer. This finding challenged the use of radical abdominal hysterectomy RAH in such cases and demonstrated the superiority of radiotherapy and chemotherapy in terms of overall survival.
Later, Avenzoar described a total extirpation of the uterus [ 2 ], and in , Giacomo Berengario da Carpi performed a partial hysterectomy in a case of prolapse [ 3 ]. Conrad Langenbeck achieved the first successful planned vaginal hysterectomy in for endometrial carcinoma, while Charles Clay was among the earliest successful practitioners of abdominal hysterectomy in Europe [ 4 ].
Wilhelm Alexander Freund performed the first known abdominal extirpation of a cancerous uterus in , and he subsequently standardized the technique for total abdominal hysterectomy.
The primitive form of radical hysterectomy was first described in by John Clark and Emil Ries Chicago after discovering cervical cancer in the tissues and lymph nodes beyond the excision limits of the standard hysterectomy [ 5 ]. Ernst Wertheim , an Austrian gynecologist, was a pioneer in the history of the surgical treatment of cancer.