Official websites use. Share sensitive information only on official, secure websites. Lam kp. To compare risk of dementia after age 50 by HIV status among individuals in a primary care setting. Observational cohort study; participants were identified from β and followed through The study setting was Kaiser Permanente Northern California, an integrated healthcare delivery system in the U.
Incident dementia diagnoses and baseline data on sociodemographics, smoking, alcohol use, other substance use, and clinical factors were gathered from the electronic health record.
(mh=h7jT96g02yiJcs86)5.jpg "SEX ESCORT Oakland")
Unadjusted and adjusted hazard ratios HR for incident dementia by HIV status were generated using Cox proportional hazards models with age as the time scale. By age 80, After adjustment for sociodemographic, substance use, and clinical factors, including frequency of outpatient visits, the risk of dementia among PWH remained elevated vs.
Research is needed to investigate the potential benefits of targeted risk factor management or earlier cognitive screening in this population. Keywords: aging, cognitive impairment, comorbidity, dementia, HIV-associated neurocognitive disorder, substance use. The neurocognitive consequences of untreated HIV infection have been well-documented. In the U. Despite the effectiveness of ART in suppressing HIV replication and reducing cognitive impairment among PWH, its protection against neurocognitive dysfunction is incomplete.
Given that many PWH are now over age 50 and have near-normal life expectancy on effective ART,[ 18 β 20 ] a growing concern is that they will experience a disproportionate burden of dementia in later life.
