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If you need assistance accessing journal content, please contact ehpsubmissions niehs. Our staff will work with you to assess and meet your accessibility needs within 3 working days. All content is public domain unless otherwise noted. Fine particulate matter PM 2. We estimated the associations of personal exposure to PM 2. PM filters collected twice during a week were analyzed for OP, using the dithiothreitol DTT and the ascorbic acid AA assays, quantifying the exposure of each pregnant woman.
Associations of prenatal PM 2. Associations with PM 2. Prenatal exposure to OP v DTT was associated with several offspring lung function parameters over time, all related to lung volumes. Exposure to ambient particulate matter PM increases risk of chronic respiratory diseases and triggers asthma and chronic obstructive pulmonary diseases.
Although studying lung function of children in early childhood is of great interest for the evaluation of their susceptibility to respiratory diseases later in life, most previous studies 11 — 15 were limited to children older than 5 y of age, when spirometry becomes feasible.
Very few studies 8 , 10 , 16 have used noninvasive techniques that allow for the measurement of lung function in very young children, such as tidal breathing flow-volume loops analysis TBFVL , nitrogen multiple-breath washout N 2 MBW , or airwave oscillometry AOS. Yet, these techniques rely on tidal breathing, making them particularly suitable and feasible in population-based cohorts.
