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Official websites use. Share sensitive information only on official, secure websites. Abstract Potential conflicts of interest.
All other authors report no potential conflicts of interest.. Conflicts that the editors consider relevant to the content of the manuscript have been disclosed. Previous studies examining the association between male circumcision MC and human papillomavirus HPV infections have reported inconsistent results. We enrolled monogamous couples in a longitudinal study between and in Montreal, Canada.
We used logistic and Poisson regression models with propensity score adjustment to estimate odds ratios ORs and rate ratios for the association between MC and the prevalence, transmission, and clearance of HPV infections. Four hundred thirteen couples were included in our study. The prevalence OR for the association between MC and baseline infections was 0. The incidence rate ratio for infection transmission was 0.
The clearance rate ratio for clearance of infections was 0. We found little evidence of an association between MC and HPV infection prevalence, transmission, or clearance in males and females.
Further longitudinal couple-based studies are required to investigate this association. Keywords: circumcision, male circumcision, HPV, human papillomavirus, sexually transmitted infections.