To browse Academia. The median follow-up was 67 months. For high risk s The IDEA steering committee comprises two members from each group coordinating an individual trial and two members from a secretariat who coordinate combining of the data and management of the joint analysis.
Members of the IDEA agreed to combine the data from their individual trials to enable definitive. HAL is a multidisciplinary open access archive for the deposit and dissemination of scientific research documents, whether they are published or not.
The documents may come from teaching and research institutions in France or abroad, or from public or private research centers. We hypothesise that sub-types of MRD, defined by circulating tumour cells CTCs and bone marrow micro-metastasis mM have different types and kinetics of relapse.
Follow up was up to 5 years or disease progression defined as new images on CT scanning. Results: 76 patients 39 men participated, mean age 67 years, median follow-up 3. The response to chemotherapy was heterogeneous and MRD pre-treatment did not predict response to therapy. RMST for the whole cohort was 3.
There were no significant differences with respect to age or sex between the three groups. Conclusions: MRD subtypes pre-chemotherapy did not predict treatment response. Post-chemotherapy MRD subtypes were associated with the pattern of failure and time Research. A B S T R A C T Purpose Given the cumulative neurotoxicity associated with oxaliplatin, a shorter duration of adjuvant therapy, if equally efficacious, would be advantageous for patients and health-care systems. Primary end-point is relapse-free survival.
